The Impact Of Impaired Swallowing Related Quality Of Life Of Head And Neck Cancer Survivors At Tikur Anbessa Specialized Referral Hospital Addis Ababa Ethiopia 2019 G.c (mixed Method Study)

Introduction: Different research and international clinical guidelines deals about thernimportance of addressing and supporting the Quality of Life needs of individuals withrnimpaired swallowing. However, data support that the presence of swallowing impairmentrnrelated Quality of Life has not directly addressed in the reviewed studies in Ethiopia.rnObjective: This study was conducted to assess factors that affect swallowing related quality ofrnlife and it is impacts in head and neck cancer survivors. rnMethods: To achieve the objective of this study 102 patients were enrolled in cross sectionalrnstudy, of whom 7 were purposively selected for in depth interviews of qualitative study. Thernstudy was conducted from March to April 2019 G.C at the oncology center of Tikur AnbessarnSpecialized Referral Hospital, Addis Ababa, Ethiopia. The pre coded data was entered in tornEpiData version 4.4.3.1 then exported to Statistical Package for the Social Sciences version 24rnfor further cleaning, and analysis. The mean comparison analysis and multiple linearrnregression were calculated. P ≤ 0.05 took as cut of value to be significant and 95% level ofrnconfidence was constructed. For qualitative study purposive sampling technique was used.rnThe data collection process facilitated by using semi structured Amharic interview guide,rnSONY tape record and filed note. After transcription and translation, data was analyzedrnmanually using Colaizzi's 6 steps of phenomenological analysis. The trustworthiness of arnqualitative study ensured by Transferability, credibility, confirmability, and dependabilityrnResult: In mean comparisons analysis, factors which showed a mean significant difference inrna MDADI subscale were sex, marital status, working condition, medical expenses, tumor site,rntumor T stage, and treatment modality. Furthermore, in multiple linear regression analysisrntumor site which was oral cavity/ oropharyngeal carcinoma and medical expenses were arnpredictor of impaired swallowing related quality of life. Moreover, in qualitative study fourrnthemes were identified such as Daily activity, Emotional, Functional, and physicalrnimpairments. rnConclusion and recommendation: In this study finding, swallowing related quality of life inrnhead and neck cancer patients was strictly affected by different factors and it had an impact inrntheir life, so measurement should be taken to improve it.

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