The TRIPS agreement provides obligatory substantive minimum standards and enforcementrnprocedures and remedies .Hence, members and acceding sates are required to make theirrnintellectual property legislations compatible with the TRIPS minimum standard of protection.rnFocusing on patent, this paper seeks to assess the compatibility of the Ethiopian patent regimernwith the TRIPS minimum standard of protection. Mostly, the assessment focused on issuesrnwhich relate with the substance of patent. To this effect, relevant legislations and administrativernand court practice are assessed in light of the TRIPS minimum standards of protection.rnAdditionally, this paper tries to sort out the way outs, to minimize or alleviate the negativernimpact of the TRIPS agreement, in the upcoming Ethiopian WTO accession.