This study was intended to examine the effects of marketing mix elements programrnon brand loyalty in context to Ethiopian Airlines S.c. as the leading Pan African airrnline and as its vision to be the world class airline in its 15 years strategic plan, thernairline is facing a tough competition with the rivals in the industry. Its marketingrnactivities can be examined in relation to brand loyalty of the organization becausernbrand success has power to allow marketers to gain competitive advantage. The studyrnused a quantitative research where a questionnaire was administered torninternational passengers of Ethiopian Airlines who used Addis Ababa Bolerninternational airport during the data collection time by employing sample sizerndeterminants like: confidence level, confidence interval and population. Arnsystematic sampling technique was used. The questionnaire consisted of factorsrnlike; brand loyalty, product, place, price and promotion. 420 questionnaires hasrndistributed and out of 402 recollected respondents 379 are considered as validrnrespondents for further investigation. The study is quantitative research approach andrnthe collected data are analyzed by scale reliability for questionnaire scaling validity,rndescriptive statistics, factor analysis, Pearson correlation analysis and multiplernregression analysis with a view to know that at what level both marketing mix andrnbrand loyalty are related with each others. The collected data revealed that there hasrnbeen a positive effect and positive relationship among different dimensions ofrnmarketing mix elements and brand loyalty of Ethiopian Airlines S.C. This studyrnindicates on selectivity of right marketing activities to suit the particular business atrna particular time and then to use it at particular situation. Further research can bernheld with more samples by extending the area of research