The Effects Of Coriandrum Sativum Seed Extracts On Hyperglycemia Lipid Profile And Renal Function In Streptozotocin Induced Type - 2 Diabetic Swiss Albino Mice

Background: Convectional drug treatment for diabetes mellitus carries risks that lead tornmany adverse effects such weight loss, hypoglycemia and many others. Ethiopia is richrnin natural resources and medicinal plants useful in the treatment of diabetes.rnAim of the study: To investigate the effect of Coriandrum sativum seed extracts onrnhyperglycemia, lipid and renal profile in streptozotocin induced diabetic mice.rnMethods: Thirty six male Swiss albino mice were kept in six different groups for 21rndays. Group I served as normal controls; Group II served as diabetic control; Groups III,rnIV and V were given 300 mg/kg, 400 mg/kg and 500mg/kg of Coriandrum sativum seedrnextracts (70% ethanol), respectively; and Group VI received 5mg/kg glibenclamide drug.rnThe effect of extracts on hyperglycemia, lipid profile and renal function were tested byrnchemistry analyzer. Results were analyzed using one way ANOVA at a 5% level ofrnsignificance.rnResults: The fasting blood glucose level was significantly (p

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