A Randomized Community Trial Of Three Alternative Oral Rehydration Therapies In Sululta District Addis Ababa Administrative Region

This is a randomized community trial which was carried out torncompare the relative effectiveness of three modes of ORT in under-rn5 children with acute diarrhea; to identify the factors associatedrnwith compliance and to assess mother's perception of ORTS. Thernthree ORTS were GORS(n=98), prepacked CBORS (n=90), and home madernCBORT (n=103). These alternative ORT therapies were compared inrnterms of mean weight gain and frequency and duration of diarrhea.rnThe CBORT group was equal to or better than the GORS or CBORS inrnterms of mean weight gain at 24, 48, 72, and 96 hrs following thernonset of treatment.rnThe mean frequency and duration of diarrhea were significantlyrnhigher in the GORS group. Increased feeding frequency wasrnassociated significantly with higher mean weight gain. Mothers'rncompliance and child acceptability were higher in CBORT whenrncompared to GORS children and similar to the CBORS children.rnMothers' perceptions of ORT as "food and medicine" was found to bernan important factor associated positively with caretakers' ORTrncompliance and child weight gain. This study suggests that beliefsrnof causation might influence mothers' compliance.rnIt is concluded that home-made CBORT is as effective as GORSrnor CBORS and more acceptable in the treatment of ACD. Thernimplementation of well monitored, community based CBORT programs inrnEthiopia are recommended.

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