The study was primarily aimed at examining the psychological and social adjustmentrnof epileptic and diabetic adolescents as compared with 'healthy ' group ofrnadolescents. Moreover, the study also aimed at further investigating into the role ofrnsome demographic variables (age, gender), clinical variables (illness duration, healthrnattack frequency) as well as attitude towards illness for the psychological and socialrnadjustment of the epileptic, diabetic and 'healthy' group of adolescents who took parIrnin the study. Data were collected by way of questionnaires from a total of J 56rnconveniently selected adolescents (52 epileptic, 52 diabetic, and 52 'healthy' .rnadolescents that were matched for age and sex) from two local hospitals and threerngovernment schools in Addis Ababa. The data were analyzed by making use of anrnindependent I-test, one way ANOTfA, Scheffe 's procedure, and mean comparisons.rnThe findings of the study revealed that adolescents with epilepsy had morernpsychological and social adjustment problems compared with 'healthy' as well asrndiabetic adolescents. Diabetic adolescents, on other hand, exhibited relatively similarrnpsychological and social adjustment outcomes as the 'healthy' adolescents. Amongrnepileptic adolescents, a relatively higher seizure frequency and unfavorable altituderntowards illness were found to be significantly associated with psychological andrnsocial adjustment problems. However in diabetic adolescents, except the femalerngender that was significantly associated with psychological adjustment problems,rnnone of the studied demographic variables, clinical variables as well as attituderntowards illness demonstrated association with the adolescents' psychological andrnsocial adjustmentrnEpileptic adolescents seemed to endure more compromised psychological and ocialrnadjustment problems. To this end the study primarily recommended the integration ofrnpsychosocial support services with medical services. Moreover, making accessiblernappropriate epilepsy related information to the adolescents was sugge 'ted alongrnmany other recommendations.