Some Aspects Of The Organic Chemistry Of Sulphur

n t h i s report, the Wmgerodt-Kindler reaction has been reviewed, and a. variant of the reaction has "been developed. In t h i s , good yields of thioamides have been obtained "by reaction of aldehydes or ketones with s a l t s of v o l a t i le amines and anhydrous sodium acetate in dimethylformamide at moderate temperatures, thus avoiding the conventional use of pressure vessels and high temperatures. The thioamides with alkyl halides give S-alkylquaternary s a l t s , which have been reacted with various nucleophilic reagents: hydrazine hydrate, sodium borohydride and diazomethane: giving interesting products.

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