A study on cattle milk production, processing and marketing was carried out in Enderta district, which is one of the four districts in the southeastern administrative zone of Tigray National Regional State, with the objective of studying the existing cattle husbandry and milk production systems, assessing cattle milk handling, processing and marketing as well as the constraints of milk production and marketing in the study area. A four stage sampling was used to select 150 households from the two livestock production systems of the district (transhumance and sedentary livestock production systems). Data was collected through questionnaire interview, group discussion, discussion with key informants and farm visit. The average landholding of respondents was significantly (p