Anti-epileptic drugs (AEDs) are the primary therapeutic modes for epileptic patients and have been demonstrated to control seizure, which decreases morbidity and mortality associated with epilepsy. There is a paucity of data on treatment outcome among epileptic patients in resource poor settings....
Effective prevention of mother to child transmission (PMTCT) of HIV programme can reduce mother to child transmission (MTCT) of HIV from 20-45% to < 2%. This study was aimed to assess effectiveness of PMTCT programs through determination of the outcome of HIV exposed infants at Asella teaching and...
Background: Withania somnifera (Local name ‘Gisawa’) is used in folkloric medicinernfor the management of hypertension in different parts of the world including Ethiopia,rnthis may be due to its diuretic activity. However, it has not been yet scientificallyrnvalidated for its efficacy...
Antimicrobial therapy demands an initial clinical evaluation of the nature and extent of the infective process and knowledge of the likely causative pathogen(s). This assessment should be supported, whenever practical, by laboratory investigation and its susceptibility to antimicrobial agents...
Based on traditional claims, leaves of Becium grandiflorum were investigated for their potential wound healing activity using excision and incision wound models. In addition histological analysis, antiinflammatory and antibacterial activity of the leaves was performed. Wound healing activity was...
The search for new anti-inflammatory agents from the huge array of medicinal plant resources is intensifying because currently available anti-inflammatory drugs pose a major problem including induction of gastric or intestinal ulcers as well as cardiovascular side effects during their clinical use....
The emergence of new prevention methods has increased the optimism towards achieving a more effective control over the AIDS epidemic, as these methods have shown the potential to promote significant reductions in the number of new infections. An important part of this optimism relates to the...
In spite of tremendous reduction in malaria-associated morbidity and mortality achieved during the last decade, malaria still remains a major global public health problem accounting for about 219 million infections and 0.66 million deaths in 106 malaria-endemic countries in the year 2010....
Currently the two most commonly used glomerular filtration rate estimating equations for drug dosing are the Modification of Diet in Renal Disease (MDRD) and Cockcroft-Gault(CG) formula. However there is still a concern about whether to use MDRD interchangeably with CG for drug dosage adjustment....
Moringa stenopetala Bak F.is commonly used in folk medicine as a single drugrnremedy to treat various aliments like; hypertension, headache, stomach disorders,rnasthma, diabetes and malaria. However, the use of the herb for treatment of pain andrninflammation has not been scientifically...
Dovyalis abyssinica locally known as “Koshim†is traditionally used to treat conditions such asrnhemorrhoids, ulcers and swelling of the throat. The toothbrush sticks are also reported to be usedrnfor oral hygiene. There is also a traditional claim that the fruits of D. abyssinica...
Background: The Human Immunodeficiency Virus (HIV) destroys and impairs the function of immune cells which results in increased susceptibility to a wide range of diseases. HIV continues to be a major global public health issue, having claimed more than 34 million lives so far. Globally there were...
Diabetes mellitus is one of the most common chronic diseases nearly in all countries and the burden continue to increase especially in developing countries. Current treatment interventions have been hampered by drawbacks like high costs, inaccessibility, and potential adverse effects. Hence it is...
Lantana camara L. is one of the medicinal plants traditionally used for the treatmentrnof diarrhea in Ethiopia. Although the antidiarrheal activity of the crude extract of thernleaves of this plant was evaluated elsewhere, no work has been performed in thernEthiopian plant. The aim of this study...
Background: Despite massively used in different settings, about half of antimicrobial agents prescribed to hospital in-patients were considered inappropriate. Such malpractice and excess use has been associated with increased mortality, adverse drug reactions, financial cost and the development of...
Malaria is one of the world’s most deadly infectious diseases. Spread and emergence ofrnantimalarial drug resistance is the major challenge that endangers all the recent gains in malariarncontrol. Medicinal plants are the key source of new effective antimalarials. Syzygium guineensernis...
Warfarin monitoring poses challenge to the treatment of thromboembolic disordersrnbecause out-of-range INRs which is encountered as a result of changes in numerousrnfactors. The fluctuation of INR in some patients might be dangerous because of thernnarrow therapeutic index of warfarin. The...
The purpose of the study is to analyze the relationship between Ethiopia's economic growth (RGDP) and trade liberalization (OPEN), using the time series data during 1971/72-2003/04. In the estimation of the long run and the short run relationships among the variables, the newly developed ARDL-ECM...
Ethiopia is one of the least developed countries with high incidence of poverty. Poverty reduction has been the center of development strategy in the country. Microfinance program on the other hand have been accepted as instruments in fighting against poverty through out the world. Since 1996,...
This study has analysed time-series models of trade balance and real exchange rate in therneconomy of Sierra Leone. More specifically, an attempt has been made to analyse thernimpact of exchange rate misalignment on the trade balance. The study also examines thernrole of real and nominal...