Adolescents are alarmingly becomes sexually active at younger age. The socioeconomic, familyrnatmosphere, peer pressure, individual life experience and other factors predisposed them to earlyrnonset of sexual activity. Premarital sexual activities of adolescent was accompanied with risk ofrnunintended pregnancy, abortion, STDs including HIV/AIDS due to lack of factual informationrnand knowledge of reproductive and sexual health issue.rnThe major purpose of this study was to investigate factors which influence female adolescentrnsexuality among in school adolescents in Woreta town. In order to assess the objective of thernstudy cross-sectional survey study design was used which includes quantitative method using arnpre-tested written questionnaire and focus group discussion used to collect qualitative data as arnsupplement of quantitative. The sampling technique employed for this study was stratifiedrnsampling procedure. Data were collected from 660 females adolescents aged 12-19 years whornare considered as adolescent in this study.rnThe statistical tools that used to analyze the data include uni-variate, bivariate and multivariaternanalysis. Univariate used to describe the adolescents and parents variables. The chi-square testrn(bivariate) was used to establish the association between the independent variables and sexualrnbehavior (dependent variable). Binary logistic regression model was used to analyze the effectsrnof the explanatory variables on the female adolescent sexuality.rnThe study revealed that 36.1 percent of unmarried female students ever had sex. As reported byrnrespondents the main reason for having sex for the first time was the desire to marry and lovernaffairs. 28.9 per cent of sexually experienced female adolescents were ever use of contraceptivernand 21.8 percent used condom at first sexual intercourse. The finding of the study showed thatrnage, education level, religiosity, living arrangement, mother education and occupation, fatherrneducation, peer pressure, self efficacy, mother-adolescent communication and respondentrnattitude toward premarital sex were associated to female adolescent ever had sex. Atrnmultivariate level, the finding of the study depicted that adolescents discussed with their motherrnabout sexual related issues were less likely to be sexually active than those who had neverrndiscussed with their mother about sexual related issue. Female adolescents who have no sexuallyrnexperienced friends were 15.2 percent less likely to have had sexual intercourse relative to thosernwho have sexually experienced friends.rnAdolescents in this study were found to involve in sex at early ages and most of whom do not userncontraceptive. Thus, the need to initiate comprehensive sexual and reproductive health programsrntargeting adolescents and strong information education communication and interventionrnprograms by all concerned bodies will be recommended. It also further noted that the neeforrnparental empowerment have to be emphasized to enable them to cope with the challenge ofadolescent life.