Seroprevalence Of Helicobacter Pylori Infection And Its Risk Factors Among Adult Patients With Dyspepsia In Hawassa Teaching And Referral Hospital South Ethiopia

Background: Helicobacter pylori is a curved gram-negative bacteria which causes gastritis andrnpeptic ulcer disease. It is also an important risk factor for the development of gastric cancer andrnmucosal associated lymphoid tissue lymphoma. Many studies revealed that the prevalence ofrnHelicobacter pylori infection varies with geographical region, socio demographic characteristicsrnand environmental conditions of the studied population. In addition, it is more frequent inrndyspeptic patients than normal individuals and dyspeptic symptoms accounts 10% of hospitalrnadmission in Ethiopia.rnObjective: The main objective was to determine the seroprevalence of Helicobacter pylorirninfection and its risk factors in adult patients with dyspepsia.rnMethods: A case control study was conducted between December 2010 and February 2011 on arntotal of 106 patients at Hawassa Teaching and Referral Hospital, South Ethiopia. The presence ofrnantibody against Helicobacter pylori was determined serologically and a face to face interviewrnwas taken to assess the contributing factors for the infection. Ethical clearance and informedrnconsents were obtained before data collection. Logistic regression was used to estimate oddsrnratio (crude and adjusted with 95% confidence interval) of positive responses to the different riskrnfactors. Comparison between groups was compared with Chi-square and a P-value of 0.05). The seroprevalence in participants thatrnhave family size > 5 was 71.4 %( 45/63) and 48.8 %( 21/43) for family size < 5 (AOR=2.6 (3.97-rn7.127) p

Get Full Work

Report copyright infringement or plagiarism