Factors Associated With Obstetrics Mortality In Intensive Care Unit Of Addis Ababa Public Hospital In 20202021. (a Hospital Based Case Control Study)

Background: Obstetrics mortality in intensive care unit (ICU) is high in low income countriesrnlike Ethiopia. The indications of admission are Preeclampsia/ Eclampsia, postpartumrnhemorrhage, and puerperal sepsis but, patient outcomes subsequent to intensive care unitrnadmission are lacking. rnObjectives: To assess factors associated with obstetrics mortality in ICUs’ of Addis AbabarnPublic hospitals, Ethiopia from October 2020 – May 2021. rnMethods: A hospital based unmatched case control study was conducted on obstetrics patientsrnadmitted to Addis Ababa Public hospital’s intensive care unit from October 2018 to Novemberrn2020. Data from 75 cases (died) and 150 controls (survived) were collected using simple randomrnsampling technique. Multivariable logistic regression analysis was done; Odds Ratio andrnConfidence Interval (OR and 95% CI) were computed using SPSS version 26. P value < 0.05rnwas taken as statistically significant. rnResult: Obstetrics mortality in intensive care unit was high and accounts 27% from the total ICUrnadmission. Severe pre-eclampsia AOR: 6.33; 95% CI: 2.25-17.79, peurpral sepsis AOR: 4.51;rn95% CI: 1.68-12.15, age greater than or equal to ( ≥ 35) AOR: 4.09; 95% CI: 1.42-11.77,rnabsence of antenatal care: AOR: 3.74; 95% CI: 1.03-13.5, maternal coexisting diseases AOR:rn5.2; 95% CI: 2.22-12.16, and severe GCS at admission AOR: 3.78; 95% CI: 1.21-11.79 werernsignificantly associated with obstetrics mortality in Addis Ababa Public Hospitals intensive carernunit. rnConclusion and Recommendation: Advanced maternal age (≥35 years), loss of antenatal care,rnpeurpral sepsis, severe pre-eclampsia, pre-existing medical comorbidities and severe Glasgorncoma scale (GCS) during ICU admission were the most significant factors associated withrnobstetrics mortality in intensive care unit. It is recommended that all pregnant women shouldrnhave antenatal care so that preeclampsia and maternal comorbidies will be early diagnosed and rntreated.

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