Prospective Cohort Study On Effect Of Timinig On Fluid Administration For Prevention Of Spinal Anesthesia Induced Hypotension In Obstetric Mothers At Ghandi Memorial Hospital December 2016 To February 2017 Addis Ababa Eth

Introduction: Neuraxial anesthesia remains the preferred choice for Cesarean deliveries acrossrnthe world. Hypotension is the physiologic consequence of spinal anesthesia and can have arnpotentially deleterious maternal and fetal impact. Measures to decrease the incidence andrnseverity of maternal hypotension include left uterine displacement, fluid preload, fluid co-load,rnprophylactic vasoconstrictors, trendelen burg position and leg elevation. Acute hydration hasrnbecome the cornerstone of prophylaxis of hypotension in obstetrics previously but recentlyrnstudies showed that co-loading also may be better option in prevention of spinal inducedrnhypotension.rnObjective: To compare crystalloid preload and coload for the prevention of maternalrnhypotension in pregnant mothers undergoing elective cesarean section under spinal anesthesia.rnSecondary outcomes studied included requirement of vasssopressor for treatment ofrnhypotension, maternal nausea and vomiting and neonatal APGAR scores.rnMaterials and Methods: Prospective cohort study design;96 parturients, American Society ofrnAnesthesiologist (ASA) physical status 1 or 2, with uncomplicated pregnancies scheduled forrncesarean section under spinal anesthesia were involved into two groups. The preload grouprntakes fluid over 20 min before the placement of spinal block; while the coload group receivedrnfluid rapidly starting as soon as CSF was tapped. Independent sample t test, Chi-square test orrnfisher exact test were used and p value

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