In this project two ligands 2,4,6-tris(hydroxylamino)-s-triazine (THASTZ) and 2,4,6-rntris (hydrazino)-s-triazine (THSTZ) were synthesized.rnSuspension of THASTZ in methanol and THSTZ in acetonitrile was used to synthesizernmetal complexes of VO(II), Ag(I), Cu(I), Cd(II) and Hg(II) They have beenrncharacterized on the basis of analytical, thermal (DSC-TGA), magnetic susceptibility,rnconductance, IR, NMR, UV-VIS spectral studies. The conductivity measurement studiesrnshow that the metal complexes are non-electrolytes and the chlorides (no chlorides inrnAg (I) and VO (II) complexes) are coordinated in the inner sphere of the metalrncomplexes. Except in DMSO both ligands (THASTZ and THSTZ) are insoluble in mostrncommon solvents unless heated. For both ligands (except for Ag (I) complex, which isrn3:1 ratio) the metal to ligand ratio in the complexes is 1:1. The data shows that Hg (II)rnand Cd (II) complexes form octahedral while VO (II) form distorted octahedralrncomplexes, where as Ag (I) and Cu (I) show tetrahedral geometry.rnAll data have confirmed the formation of THASTZ, THSTZ and their correspondingrnmetal complexes. Antimicrobial activity tests against salmonella typhi and staphlococusrnaureus of THASTZ, THSTZ and their corresponding metal complexes have beenrninvestigated. The result shows that 2,4,6-tris (hydrazino)-s-triazine was found inactivernagainst salmonella typhi; where as 2,4,6-tris (hydroxyl amino)-s-triazine was inactive against both bacteria. Metal complexes of both THSTZ and THASTZ have variedrninhibition activities diameter against both bacteria.