Chemical Investigation Of A Red Sea Sponge Of The Genus Dysidea

A new hexachlorinated metabolite, for which thern'name dysidimide is proposed, has been isolated from arnRed Sea sponge of the genus Dysidea.rnDysidimide was the major metabolite obtained fromrnthe ethanol extract o>f the dried sponge collected nearrnMassawa, Repeated column chromatography on silica gelrnwith pet-ether * chloroform and recryatallization yieldedrndysidimide as white needle crystals.rnThe structure of dysidimide was determined by chemi- cal and spectroscopic studies including IR, MS, and IDrnand 2D NMR. The relative stereochemistry at C-4 and C-5rnwas deduced from nOe measurements on/ the 4-Acetate

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