The main objective of this study was to investigate teachers practices and challenges in the Use of Interactive White Board in the case of Diamond Academy a school located in Yeka sub-city, Addis Ababa. To achieve this objective the researcher used, both quantitative and qualitative research (mixed research) method. The targeted population was purposively selected, 75 teachers and 2 school directors of Diamond Academy. Data was collected using questionnaire interview and observation. The quantitative data was analyzed using statistical package for social sciences (SPSS) while the qualitative data were analyzed in a narrative way. The study findings revealed that the factors that hinder teachers from using the interactive white board are, lack of technical support for teachers and absence of trainings from experts in using interactive white boards and also teachers lack of confidence, negative attitudes towards the IWB, time constraint, work load to prepare lessons coinciding with the IWB, lack of skill, lack of preparation were identified as challenges to use the IWB to bring the intended positive outcomes on students with the aid of the interactivity nature of the IWB. The results of this research suggest the school needs to provide technical support for teachers and increase the number of technicians. Applied pedagogical trainings from experts in using interactive white boards should be provided for teachers. School leaders should include digital tool use in teachers CPD programs.