Institutional collaboration is the challenging aspect in DRM in Ethiopia. Due to this, there is anrnincreasing nature of disasters in frequency and number in Ethiopia from time to time. Therefore,rnthe main purpose of the study was to assess institutions collaboration in managing disaster risksrnin Ethiopia since 2015. To examine this, qualitative research approach with descriptive casernstudy design was used. The data was collected by using both primary and secondary datarnsources. The subjects who participated in the study were selected by using purposive sampling.rnSeventeen interviewees were interviewed until the point of saturation. Directors, consultants andrnexperts from NDRMC were interviewed since they have adequate knowledge about the issue.rnSemi structured KII and document review were data instruments employed for data collection. Arncombination of content and interpretive analysis was used to explore the collected data. Thernresult indicated that even though large number of lead sector institutions and humanitarianrnpartners were participated in DRM practices in Ethiopia, their collaboration was focused duringrnthe time of emergency response. Based on the finding, absence of due attention on prevention,rnmitigation and reconstruction practices towards disaster risk reduction were the main challengernthat institutions face in collaboration towards DRM practices in Ethiopia. In this regard, thernnext points shall be taken in to account to enhance the role of institutions in DRM in Ethiopia:rnfocus on pre-disaster prevention and mitigation; create center of excellence that give muchrnemphasis on indigenous knowledge; develop the culture of tolerance and adopt DRM laws thatrnenforce line ministers to do their roles as prescribed in the 2013 policy and strategies ofrnNDRMC.rnKeywords: DRM practices, humanitarian institutions, institutional collaboration, lead sectorrninstitutions, opportunities and challenges, Ethiopia