Micro and small enterprises are essential for creating jobs for low income groups. Food processing andrnservices are one of the sectors of MSE.The delivery and success of these services are inextricably tied withrnthe quality of food processing. This in turn is reflected by the knowledge, attitude and practice the foodrnhandlers have. So, determining the level of KAP and assessing the work environment of the food handlersrncould contribute in improving the service delivery and quality of this sector. Thus, the over all objective ofrnthe study was to analyze the food security status and food safety KAP of MSE food handlers in five selectedrnworedas of Lideta Sub - City, Addis Ababa. Cross-sectional survey was done among the MSE food handlersrnin the study area with a total sample size of, n=255 participants. Questionnaire was used to collect datarnand data was collected from January through march. Purposive sampling technique was used to includernworedas with high number of MSE food handlers. The analysis was done using descriptive statistics andrnchi-square was used to determinet significance of association between variables of interest. The resultsrnshow that about 22% of respondents were food secure, 45% mildly food insecure, 27% moderately foodrninsecure and 6% severely food insecure. The total food handling knowledge, attitude and practice (KAP)rnof MSE food handlers were about 73%, 94% and 20%, respectively. The total personal hygiene KAP wasrnabout 23%, 97% and 29%, respectively. Water and sanitation KAP were about 31%, 96% and 35%,rnrespectively. Most of respondents stated that there was no shower, unclean toilet, lack of hand washingrnfacilities in the work place. Generally, the result has shown relatively higher food handling knowledge.rnHowever, poor knowledge and practice in but high positive attitude towards food safety issues. Poorrnhygienic practices together with poor sanitary conditions in MSE food handlers can contribute tornoccurrences of food borne illnesses and lack of customers which inturn leads to food insecurity. To improvernfood safety KAP and food security status of MSE food handlers, providing appropriate training about foodrnsafety and providing them with suitable working environment is of paramount importance.