Cholinesterase Status Of Some Ethiopian Pest Control Workers Exposed To Organophosphate Pesticides

A study was conducted in 430 pest control workers with that ofrn161 comparable controls. The health risks and associatedrnmorbidity from occupational exposure to organophosphate (OP)rnpesticides was determined and factors ttat may contribute torna greater pesticide exposure were identified.rnPlasma and RBC cholinesterase (GhE) activities were determinedrnusing electrometric methods. Symptoms of OP poisoning and riskrnfactors for exposure associated with pesticide use werernassessed through a questionnaire, developed based on the WHOrn(1982) and WHO-UNDP (Maroni et al 1986) recommendations. Tornevaluate the possible liver dysfunction, plasma levels ofrnalkaline phosphatase (AP) and gl utamic pyruvic transaminasern(i;PT) ',.;ere determined using diagnostic ki~s number 6391 anrjrn14442520 respectively.rnSignificantly lower plasma and RBC GhE activities were foundrnin the exposed workers compared to the controls (P

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