The effects of six fungal isolates; DLCO-AA-S, DLCO-AA-14, IlTA 18, IMI 330189, DLCOAA-rn83 and DLCO-AA-I09 were evaluated in the laboratOlY for their pathogenicity to adults,rnSth and 6th lalval instars of both the greater wax moth (Galleria l1lellollella) and lesser waxrnmoth (Achroia grisella). Conidial dilutions were prepared in O.S% Tween 80. The adults ofrnboth species were treated by spraying while dipping the lalvae in varied fungal concentrationsrnranging from 2xl04 to 2xlO7 conidia/m!. Assessments of lalval infection of both the greaterrnand lesser wax moth was made daily for 14 days before entering the pupal stage afterrntreatment. MOltality assessment for the lesser wax moth adults was made daily for 8 days postrntreatment. Adults of both the greater and lesser wax moths were found to be susceptible to allrnfungal isolates and concentrations, ranging from 2xl04 to 2xl07 conidia/m!. Comparison ofrnmortality results in adults of the greater wax moth at 2xl04 conidia/ml revealed that infectionrnof over 90% could be achieved in 13 days after inoculation. Similar comparison with thernadults of the lesser wax moth showed that over 78% mortality could be achieved by day 8 afterrntreatment except isolate IMI33089 that caused low mOltality of 67.0S%. Comparison ofrnmOttality results of the Sth larval instars of both species of wax moth at 2xl07 conidia/mlrnshowed varying degrees of vimlence among the fungal isolates. With the Sth lalval instars ofrnthe greater wax moth, isolate IITA 18 caused percentage mOttality of 68.S2% while withrnisolates DLCO-AA-S and DLCO-AA-14 a cumulative percentage mortality of61.11 % wasrnrecorded in the lesser wax moth by day 14 of post treatment. Low mortality in the Sth larvalrninstars of both species was recorded with isolate 1MI 330189. With the greater wax moths Sthrnlalval instars, mortality in the control was less than 2 % while in the lesser it was less than 4%.rnResults on percentage emergence of the adults from pupae of the greater wax moth adultsrnshowed no significant difference (P > O.OS) between the different fungal isolates and controls.rnWith the lesser wax moth a slight difference in emergence of adults from pupae was observedrnbetween 2xlO7 conidia/ml and the controls. With all fungal isolates and concentrations used,rnpercentage emergence of over 86.1 % was obselved in the greater and lesser adults. Thisrnshowed that, the isolates at the different fungal concentrations had no effect all adultrnemergence when applied on the 6th instars. LaboratOlY experiments were also conducted torninvestigate host specificity of two isolates of Metarlzizilll1l spp (DLCO-AA-83 and IMIrn330189) and I Beallveria spp (UTA 18) all deuteromyceteentomopathogenic fungi that were tested as entomopathogenic agents against the honeybeesrn(Apis melli/era (Ethiopian race). Each isolate was applied topically by spraying 10mi of2x107rnconidia/ml into the beehives. Isolate UTA 18 caused 0.5% moriality of the treated surfacernsterilized honeybees, isolate DLCO-AA-83 resulted in 1% mortality of the treated sUifacernsterilized honeybees and isolate IMI 330189 had no effect on the honeybees. In cases wererninfection with the applied fungal isolates occurred, fungal growth on the cadavers wasrnobserved after surface sterilization. Therefore, the present study confirm the pathogenicity ofrnall the tested isolates against the adu Its of the greater and lesser wax moths and 4 of thesernisolates in i.e. isolates in degree of virulence. Isolates UTA 18, DLCO-AA-14, DDLCO-AA-5rnand D LCO-AA-83 for the greater wax moth while isolates DLCO-AA-5, D LCO-AA-14 &rnDLCO-AA-83 and isolate UTA 18 for the lesser 5th larval instars as potential microbial controlrnagents for the management of the greater and lesser wax moths.