Clerkship is a clinical experience in the education of a student of the health professions in whichrnhe or she is introduced to the practical care of patients with particular illnesses orrncharacteristics. This study aimed to assess the challenges experienced by pharmacy students asrnthey start their clinical training in the context of private colleges in Addis Ababa. The studyrnfocused on final year undergraduate pharmacy students during their hospital clerkshiprn(attachment) in AA. Using descriptive research method, this study identified lack of supervision,rninopportune feedback and dispiriting current environment were the key challenges of final yearrnundergraduate pharmacy students during their hospital clerkship (attachment) in private healthrncolleges in AA. This study helps students gain familiarity with clerkship expectations and settingsrnand it generally focus on orienting students to workplace logistics and roles and helps tornenhance their clinical skills. It recommends that the necessity of careful preparation for clinicalrnclerkship, uncertainty when starting clerkship lasted only a few days transition from pre-clinicalrnto clinical training went smoothly and a need time to adjust to the new environment.