The aim of this research paper is to assessing the effect of motivation on Job satisfaction andrnlead to Employee Performance by the case organization, Commercial Bank of Ethiopia.rnMotivational factors (Salary and Benefit, Promotion, Recognition, Work Content, and WorkingrnCondition) are assessed in order to find motivation effect on job satisfaction. The study takes jobrnsatisfaction as a mediator between motivation and employee performance. The study wasrnconducted based on the data gathered from sixteen branches of commercial bank of Ethiopia. Arnmixed research approach was used to answer the research questions that emerged through thernreview of existing literature and the experiences of the researcher in respect to effect ofrnmotivation on job satisfaction and lead to employee performance. The study statisticallyrnanalyzed data obtained from the survey questionnaire. A research framework developed basedrnon Herzberg Two Factor Theory and modified by the researcher is used to guide the study. Thernresult of the study indicated that job satisfaction is highly lead employees to performance inrnother word job satisfaction is a significant and strong mediator between motivation andrnemployee performance but related to motivation employees are not satisfied and motivated withrnthe current procedure carried out by the bank. It revealed that they are mostly not satisfied withrnthe promotion, recognition and work content practice of the bank. The study suggests differentrnmeasures include: drafting and implementing clear and appropriate career advancementrnprocedures, providing proper and timely recognition as part of the system, the basis ofrnmotivational procedures taken up by the organization should follow the interest of employees,rnand shaping and implementing appropriate motivational techniques in order to satisfy itsrnemployees and to get high employee performance In order to achieve organizational objectives