Losses in the urban water supply networks have become a growing concern and there are severalrnalternatives for the quantification, detection and monitoring of water losses. However, water loss is arngreat challenge in developing countries including Ethiopia as well as Debre Brehan town. Peoples dornnot have enough access to safe and reliable water coverage due to highly water loss in the distributionrnsystem and other utility problem. Therefore, this study mainly focuses on to assess the status of waterrnsupply coverage and water losses in Debre Brehan town. Statistical analysis with regards of fieldrnobservation, different literature revision, pressure measurement and discussions with water servicernpersonnel were conducted to analyze the water supply coverage and water loss in the town. WaterrnCAD software was adopted to examine the hydraulic parameters and water supply elements in therndistribution network. The finding of this study showed that the average connection per family andrnaverage daily per capita water consumption of the town was estimated in the order of 32% and 23.24rnl/c/d respectively. As water loss estimation result from the total production of water in the town aboutrn37.40% of is non-revenue water. Among this, 6.78% is real loss that includes leakage and pipe burst.rnWhereas, 30.62% was apparent loss more considerable and accounted for meter inaccuracy, poorrnmaintenance practice, legal unbilled connection and illegal connection. Moreover, from the modelrnanalysis result different problems were observed. These were poor efficiency of pumps and storagerntanks, high and low pressure beyond to the recommended value. In general, the main reasons for thernlow water supply coverage of town was poor water network management, lack of attention and budgetrnto develop additional water source, high level of water loss and low performance of the existingrndistribution system. Thus, well organized network management practice, giving more attention tornwater loss and reduction strategies, constructing additional source of water and installing standbyrngenerator at all existing pump station are some important remedial measures to improve the waterrnsupply coverage of the town.