Humanitarian Logistics is a very important cluster of activities during emergencies due to natural orrnman-made disasters in an effort to prevent loss of lives and property. However, the subject is not wellrnresearched compared to the business logistics in profit making organizations where profit is theirrnmain reason of existence. The main objective of this study was to assess the practices, identify factorsrnaffecting the humanitarian logistics performance and measure the performance of a selected nonprofit making international organization, International medical corps Ethiopia and try to contributernto the research family in the field. The main research design applied for the research was a descriptivernand explanatory type of research design. This study is to combine the practice, internal & externalrnfactors together and examine their effects using survey data analyzed through empirical study andrnidentified seven statistically significant variables both from internal & external factors. Descendingrnfrom highest to lowest per their significance level factors are listed as: lack of collaboration, adequaterndonor funding, infrastructural situational factor, un availability professional staff, governmentrnsituational factors, and Measuring the performance of humanitarian logistics and lack of recognitionrnof logistics. Moreover, so far, these variables were not investigated in the international medical corpsrnEthiopia context and hence this study is the first and the original in the case of this organization.rnFinally, this study has filled to important research gaps: the empirical methodological gap thatrnprevious studies have failed but suggested to, and Assessment of the current situation in the effect ofrnlogistics performance and its associated factors at international medical corps Ethiopia.