Background; StrengtheningrnLaboratory ImprovementrnProcessrnTowardsrnAccreditationrnrecognizes laboratories where they are in the process of quality improvement; through audits andrndirect on technical assistance.rnObjective: The aim of this study was to assess the implementation status of SLIPTA in selectedrnpublic hospital laboratories in Ethiopia.rnMethods: Hospital based cross sectional study design was used to assess the implementationrnstatus of SLIPTA in four public hospital laboratories in Ethiopia. The facilities were selectedrnusing purposive technique. Their implementation status was assessed using SLIPTA standardrnchecklist, and a semi-structured questioner to identify factors during the implementation phases.rnThe current and the last audit scores of the facilities had compared against the SILPTA scorernlevel. Interview based exploratory discussion for the key informants were used. This study wasrnconducted from April to October 2015.rnResults: This finding indicated that two laboratories (lab.3 and lab.4) were improved from zerornstars [82(31.78%) and 102(39.5%) points] in pervious audit result to two stars [175(67.8%) andrn182(70.5%) points] in current audit result respectively. The other two laboratories (Lab.1 andrnLab. 2) had no changes that score zero stars with pervious audit result [94 (36.4%) and 82rn(32.56%)] to current audit result [95 (36.8%) and 104 (40.31%)] respectively. All (16/16) keyrninformants responded that they had no written plan, follow up, report of the SLIPTA program;rnand with staff attrition rate, no written duties and responsibilities.rnConclusion: Improvements were seen with Lab.3 and Lab.4 which reaching two stars from zerornstars at the WHO SLIPTA audit result within one year. These laboratories had better partnershiprnsupport that initiate or drive the laboratories and better management style when it is compare tornthe other two laboratories. The factors that affect the SLIPTA program were mainly in humanrnresources and development part that corresponding to lack of concern, commitment, dedication,rnmanagerial skill; and resistance to new approach, staff attrition rate, no written duties andrnresponsibilities and demotivation.rnKey Words: SLIPTA, WHO-AFRO, Transcription, Key Informants, Quality ManagementrnSystem