Assessment Of Platelet Count In Malaria Suspected Patients And Associated Factors In Arba Minch Health Center Arba Minch Ethiopia

Background: Malaria infection is a major public health problem and cause of morbidity and mortality inrntropical and subtropical regions of the world. It has been consistently reported as one of the three leadingrncauses of morbidity and mortality in Ethiopia. Changes in hematological parameters are likely to berninfluenced by any disease condition including endemic diseases, such as malaria. Anemia andrnthrombocytopenia are the most frequent malaria associated hematological complications and they play arnmajor role in malaria pathogenesis. The presence of thrombocytopenia in malaria positive patients hasrnbecome a highly sensitive clinical marker for malaria diagnosis. significant correlation between malariarnand the presence of thrombocytopenia is mandatory before taking it as a hematological parameter of therndisease. However in Ethiopia the relation between thrombocytopenia and malaria pathogenesis is not wellrnstudied.rnObjective: To assess platelet count among malaria suspected patients and associated factors in ArbarnMinch Health Center, Arba Minch, Ethiopia.rn.Methodology: Aninstitutional based cross sectional study was conducted in Arba Minch Health centerrnfrom February to April, 2015. Data was collected from 424 malaria suspected patients that came duringrnthe 3 months of data collection period. Using estimation of single population proportion formula andrnsequential sampling technique we selected 424 study participants. In addition data on sex, age, occupationrnand associated factors was collected using structured checklist.Data was entered and analyzed by SPSSrnVersion 20.Frequency and cross tabulation was conductedto describe relevant variables in relation to thernoutcome variables; bivariate and multivariate logistic regression analysis was conducted to identifyrnsignificant predictors based on p-value less than 0.05 with 95% confidence level.rnResult: Among 424 malaria suspected patients 117 (27.6%) [95% CI 23.3 - 31.9] were positive forrnmalaria and the rest 307(72.4%) [95%CI 68.1- 76.7] were negative. Prevalence of thrombocytopenia wasrn36.1% and among this 19.8% were malaria positive. The mean platelet count in Plasmodium vivaxwasrn163,000/μl (SD 115,000) with a range of 18,000-403,000/μl as against Plasmodium falciparum malariarn128,000(SD72, 324/μl) with a range of 33,000-311,000/μl). A significant reduction of platelet count wasrnseen in this study (AOR 15.7, P

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