Assessment Of Magnitude Severity And Determinants Of Anemia In Hivaids Patients Taking Zidovudine And Tenofovir Containing First Line Haat Regimen At Acsh Mekelle Ethiopia.

Background: Human Immunodeficiency Virus (HIV) and anemia are the major public healthrnproblems in sub-Sahara Africa. Anemia in HIV-infected individuals is associated with morernrapid disease progression and a poorer prognosis if not addressed appropriately. rnObjective: This study was aimed at determining the magnitude, severity and determinants ofrnanemia among HIV infected patients taking Zidovudine (ZDV) and Tenofovir (TDF) containingrnfirst line HAART regimen in Ayder Comprehensive Specialized Hospital (ACSH), Mekele,rnEthiopia 2019. rnMethods: Institutional based cross sectional study was conducted using both convenient andrnquota sampling method to assess prevalence, severity and determinants of anemia in ACSH,rnEthiopia from February to August 2019. Sociodemographic and clinical characteristics of 212rnHIV infected patients on ZDV and TDF containing first line HAART regimen were assessed.rnStructured questionnaire, medical records, anthropometric measurement tools (electronicrnweighing scale, adult height board), automated hematology analyzer (Sysmex XT-4000i) forrnCBC analysis and Becton Dickinson’s (BD) FACS caliber flow cytometer for the enumeration ofrnCD4 T- lymphocyte count were used. rnResults: Around one third of the study participants (33.5%, n=212) were found to be anemicrn(ZDV: 20.3%; TDF: 13.2% and P

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