Background: Viral hepatitis could be an international public health problem affecting manyrnindividuals each year, causing disability and death. Hepatitis B and Hepatitis C viruses arerncommon causes of hepatitis. Federal police crime prevention staffs are high-risk people forrnparenteral and sexually transmitted diseases such as hepatitis B virus (HBV) and hepatitis Crnvirus (HCV). Data regarding prevalence, knowledge, attitude and practice of Federal policerncrime prevention staffs towards hepatitis B virus (HBV) and hepatitis C virus (HCV) in Ethiopiarnis limited.rnObjective: Determining the prevalence, knowledge, attitude and practice of Federal policerncrime prevention staffs towards hepatitis B virus (HBV) and hepatitis C virus (HCV) in AddisrnAbaba, Ethiopia.rnMethods: Institutional based cross sectional study was conducted among 500 federal policerncrime prevention staffs, in Addis Ababa, Ethiopia from December 2018 to June 2019. Arnsystematic probability sampling method was employed. A structured questionnaire was used torncollect data on socio-demographic characteristics, knowledge, attitude and practice. All samplesrnwere tested, using a wondfo one step test strip for HBsAg and Ecotest test strip for HCV. Positivernsamples were retested by using Murex HBsAg version 3 UK ELISA kits. Data entry and analysis wasrndone using SPSS version 20 computer software.rnResults: The overall prevalence of HBV among Federal police crime prevention staffs in Addis Ababa,rnEthiopia was 4.6% (n=23/500). Of those 4.9% (n=20/407) males and 3.2% (n=3/93) of females werernpositive for HBV. The overall prevalence of HCV was 0(0%). From the total participants, 51%rn(n=255/500) did not heard about hepatitis, 61.4% (n=332/500) and 61% (n=305/500) incorrectlyrnidentified that HBV and HCV can be transmitted by feco-oral and contaminated water, 97%rn(n=485/500) were not screened and 99.6% (n=498/500) were not vaccinated. The majority of the studyrnparticipants 349(69.8%) believe that their job puts them at high risk of acquiring of HBV and HCV, 84.6%rn(n=423/5) agreed that taking of HBV vaccine is safe.rnConclusion and recommendation: The prevalence of hepatitis B viruses among federal police crimernprevention staffs in Addis Ababa was intermediate and very low hepatitis C. Majority of the participantsrnhad limited knowledge about the transmission and protection of HBV and HCV infection. Large scalernstudy is important to make generalization and conducting regular health education is essential.