Prevalence And Determent Risk Factors Of Active Pulmonary Tuberculosis In Federal Prison Administration High Security And Kilinto Appointment Prison Centers At Addis Ababa Ethiopia

Background: TB prevention and control practices in many correctional facilities were longrnneeded. Particularly attention needs to be given to screening, identifying persons who arerninfected with Mycobacterium tuberculosis or who have active TB disease. rnObjective: This study was done to assess the determinant factors for the prevalence of activernpulmonary TB among presumed to be TB individuals with characteristic symptom of TB fromrnKality High Security Prison and Kilinto Prison Centers. rnMethod: a facility -based cross-sectional study design was used to recruit 218 inmates inrnKality High Security and Kilinto Prison Centers, between April 1 and may 31rn. Inmates wererneligible for the study if they had cough for more than or equal to two weeks during the studyrnperiod. Structured questionnaire was used to collect data on risk factors of pulmonaryrntuberculosis. Sputum samples were collected from presumed to be TB inmates and examinedrnusing sputum GeneXpert and light microscopy. rnResult: From 218 examined sputum, 11/218 (5.4%) were positive. The prevalence ofrnpulmonary tuberculosis was 5.04% (11/218) and 2.8% (6/218) as detected by GeneXpert andrnmicroscopy, respectively. 5 from Kilinto Remand prison (2.29%) and 7 from Kality HighrnSecurity (3.21%) had PTB when tested with GeneXpert. From the total of 218 inmates, 92.7 %rn(202/218) were male where 11 (100%) of the PTB cases were male. In multivariate analysis,rnPrison home with less than 3 window with (AOR=3.2; 95% CI=0.9-10.31, Alcoholrnconsumption with AOR=0.50; 95% CI=3.7-2.45, having history of TB infection (AOR=5.8;rn95% CI=1.73-25.1), Age 18-45 (OR=0.15; 95% CI=0.29-0.89), had significant associationrnwith increased odds of being positive for PTB. in this study. RIF’s resistance not detected. rnConclusion: 5.4 %PTB point prevalence in this study was twice higher than the national TBrn(0.211 %) indicated by National TB Indicator survey of 2013. Detected PTB was associatedrnwith being young age, availability of window, having TB history and Alcohol consumptionrnwas found to be risk factor for PTB. GeneXpert detected more PTB in the sputum samplern(more sensitive) than microscopy.

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