Malaria-schistosomiasis Mansoni Co-morbidities And The Possible Reciprocal Effects On The Parasitological Clinical And Immunological Outcomes In Finchaa Sugar Estate Western Ethiopia

In Ethiopia where malaria parasite and Schistosoma mansoni infections are coendemic,rnthe general population is quite vulnerable both to malaria and Schistosoma mansonirninfections singly and concomitantly. However, data about the prevalence of malaria-rnSchistosoma mansoni co-infection and their reciprocal parasitological, clinical andrnimmunological effects are lacking.The aim of this study was to assess the reciprocalrneffects of malaria- Schistosoma mansoni co-infections with emphasis on parasitological,rnclinical and immunological interactions.A community based cross sectional study wasrnconducted in Finchaa Sugar Estate, western Ethiopia. Blood samples were collected byrnfinger pricking and thick and thin smears stained with Giemsa. Fresh stool samples wererncollected and processed by the Kato-Katz method. Haemoglobin level was determinedrnusing a portable spectrophotometer. Plasma was collected for cytokine assay andrnmeasurements of selected cytokines were performed using luminex IS 100 instrument.rnSchistosomal periportal and portal liver fibroses were determined by using thernultrasound assessment method. SPSS statistical software version 20 was used and Pvaluern

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