Background: Myocardial perfusion imaging is being increasingly used as a non-invasive rnimaging modality for evaluating patients with known or suspected coronary artery disease inrndeveloped countries, but information about the need and the number of complications that couldrnhave been avoided with the myocardial perfusion imaging practice has not been assessed. rnObjective: The objective of this study was to determine the magnitude of need for myocardialrnperfusion imaging, the level of unnecessary invasive coronary angiography procedures done andrncomplications that are associated with it. rnMethods: A retrospective secondary data was used where 340 patients with known or suspectedrncoronary artery disease who attended cardiac clinic of Tikur Anbessa Specialized Hospital forrndiagnosis and follow up from December 2018-December 2020 were included. rnResults: Females accounted for 34.4% (117) of the cases while 223 (65.6%) of them were males.rnThe mean age of the patients was 60.97Â±10.7 years. Diagnosis of Coronary artery disease wasrnfound in 276 (82.1%) out of the 340 patients. Symptoms of coronary artery disease were presentrnin 229 (67.4%) of the patients. Risk factors for coronary artery disease were identified in 288rn(84.7%) of the patients. Indication for myocardial perfusion imaging was present in 198 (58.2%)rnof the total patients evaluated in this study. rnConclusions: Most of the coronary artery disease patients needed myocardial perfusion imaging.rnThe absence of myocardial perfusion imaging in the study area has exposed patients forrnunnecessary invasive coronary angiography which incurs complications on patients.