Background: - oncology nurses are exposed to stressors that may contribute to compassionrnfatigue, leading to high rates of turnover, potential financial implications for organizations,rnand concerns for patient safety and employee well-being. Therefore the aim of this study tornassess the prevalence of compassion fatigue and associated factors among nurses working inrncancer centres of selected hospitals in Ethiopia. rnObjective: -The aim of this study was to assess the prevalence of compassion fatigue andrnassociated factors among nurses working in cancer centres of selected hospitals in Ethiopia. rnMethods: - Institution based cross-sectional study were conducted in nurses who werernworking in oncology unit of public Hospitals of Ethiopia. rnTotal sample sizes of 230 nurses were participated in the study. Data was coded and enteredrninto EPi data software and exported to SPSS version 23 for analysis. Descriptive statisticsrnsuch as frequencies and percentiles were computed to describe the study population inrnrelation to relevant variables. Multiple linear regression models were employed. Variables prnvalue