Background-Diagnosis of breast cancer can be stressful, impacting on multiple domain of life,rnaffecting physical status, emotional and spiritual well-being and personal relationships for thernpatient and mostly affects woman’s body image, sexuality leads to stress. In order to adapt, thernpatient used different coping methods. Variations may occur from one person to another personrndue to individual coping strategies, personality factors, and the level of social support availablernto them. In Ethiopia studies conducted so far are very limited.rnObjectives-To identify Coping Strategies of Stress in Breast Cancer Patienst at Tikur AnbessarnSpecialized Hospital, Addis Ababa, Ethiopia, 2020rnMethods-Institution based cross-sectional study design was conducted from February to Aprilrn2020 at Tikur Anbessa Specialized Hospital. Quantitative approach convenient samplingrntechnique was used and sample sizes of 264 are participated in the study. The data was collectedrnusing structured and semi structured questionnaire and analyzed using SPSS version 25. Thernstatistical analysis was done at 95% confidence and p-value of