Background -Occupational Injury (work related injury) is among major public healthrnproblems that accounts 1.5% of public health burden in terms of DALLY and anrneconomic loss of 5-10% GNP globally.Preventing or reducing work-related injuryrnamong flour factory workers are one of the key issues in improving workers health andrnsafety in manufacturing industry. This issue is relevant particularly in developingrncountries including Ethiopia.rnObjective: The aim of this study is to assess magnitude and associated factors ofrnoccupational injury among production workers in large scale flour factories in Asellarnduring the last 12 months.rnMethod: : Institution based Cross-sectional study design was conducted from March,17-rnApril 4 2015 among 412 study subjects were selected using simple random samplingrnmethod taking payroll as a sampling frame.rnData collection was done by using interviewer administered questionnaire, observationrnand record review by the Principal Investigator. The collected data were manuallyrnchecked for completeness and entered in to EP Info for data cleaning and finallyrnexported to SPSS for further analyses. Descriptive statistics and logistic regressionrnanalyses methods were employed to determine factors that may have significantrnassociation to the dependent variable. Variables that are identified as having p-value lessrnthan 0.25 on bivariate analyses were considered as a candidate to be evaluated onrnmultivariable model, and then a variable with p-value less than 0.05 on final model werernconsidered as having significant association.rnResult: The overall occupational injury prevalence rate was 24%. , exposure to excessivernheat at work was found to have positive association with accidental injury at AOR =rn2.570, P value< 0.05, 95% CI (1.12-5.91), Accordingly, those employees who wererncarrying heavy weight compared to their counterparts are at high risk of accidental injuryrnat AOR 1.432, p value 0.05 , (95% CI) (1.001-2.048),workers who have got regularrnhealth and safety supervision are more likely not to encounter injury at. AOR = 3.052, prnvalue 0.002 , 95% CI (1.507-6.181), utilization of personal protective devices in whichrnthose who are using the device are at lower risk of encountering accidental injury at andrnAOR 0.39, p-value 0.001 ,(95% CI) (0.23-0.66). One more covariate identified asrnsignificant was status of chewing chat. Employees who are chewing chat are six times atrnhigher risk of acquiring accidental injury compared to those who are not chewing chat atrnp-value < 0.05.rnConclusion - result show that work-related injury prevalence is high over the last one year.rnThe factors significantly associated with incident of injury were utilization of personalrnprotective device, handling of heavy object, excessive heat at work, Regular health and safetyrnsupervision &chewing chat