Mother- To-child Transmission Of Hiv And Associated Factor Among Exposed Infants On Follow-up In Jinka Town Health Facilities South Omo Zone South Ethiopia 2020.

Background: HIV/AIDS can affect all age groups, but is the leading infectious cause of pediatricsrnmorbidity and mortality in the world. A vast majority of HIV infections in children under the agernof 15 were through mother to child transmission. In Ethiopia, MTCT accounts for 95 percent ofrnchildhood HIV infections but risk of transmission increases significantly if the mother is untreated rnObjective: To assess rate of Mother- to - Child Transmission of HIV and associated factors amongrnexposed infants on follow-up in Jinka town health facilities, South omo zone, South Ethiopia,rn2020. rnMethodology: A retrospective cohort study was employed among 230 exposed infants in Jinkarngeneral hospital and millennium health center at Jinka. Medical records of HIV- exposed infantrnand their mothers enrolled at PMTCT clinics in the study institution and registered fromrnSeptember/2014 to August /2018 were extracted using data extraction sheet after getting ethicalrnclearance from the Institutional review board of Addis Ababa University. The data was entered inrnEpi Data 4.2 version and exported to SPSS version 25 for final analysis. Bivariate andrnmultivariable logistic regression were used to identify predictors of HIV vertical transmission.rnSignificance was considered at P-value < 0.05 in the multivariable analysis. rnResults: A total of 228 infant-mother records were included in analysis. 5.3% of HEIs got HIVrninfected vertically in the study area. Not receiving ARV prophylaxis at birth (AOR=5.8, 95% CI:rn1.02-33.53, p=0.047), absence of maternal ARV prior to current pregnancy (AOR=5.6,95% CI:rn1.14-28.1, P=0.034), mother’s advanced WHO clinical stage of HIV at enrollment to PMTCTrn(AOR: 10.5; 95% CI: 1.4,81, p=0.022) were significantly associated with mother to childrntransmission of HIV in this study. rnConclusion Infant did not received nevirapine prophylaxis at birth, mothers who were at advancedrnWHO clinical stage of AIDS, and mothers who did not received ARV prior to pregnancy were atrnhigher risk of mother to child transmission of HIV infection.

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