Strong regulatory framework enables to ensure that the manufacture, trade and use of veterinaryrndrugs are effectively regulated, and to protect and promote animal health, animal production andrnpublic health at large. To perform core regulatory functions efficiently, the regulatory bodiesrnrequire having adequate legislations and regulatory tools, appropriate organizational structure,rnadequately trained human resources, sustainable finance, and effective cooperation betweenrndifferent regulatory bodies and with other law enforcing bodies. This study therefore aimed tornassess veterinary drugs regulatory framework in Ethiopia. An archival review and expert panelrnbased qualitative study was conducted from April to September 2019. A detailed review ofrnlegislations, regulatory activity plans and reports, and human and financial resource archives wasrnconducted. Forty experts, 33 of them working in veterinary drug regulatory authority and sevenrnfrom private veterinary drug traders, were grouped in to six groups for a panel discussion.rnExperts were allowed to dialogue on each semi-structured questions until they reach consensus.rnNarrative description of the expertsâ€™ consensus and linking them with the archival reviewrnfindings were conducted to report findings. This study revealed that the federal regulatory bodyrnhad adequate human and financial resources. However, the federal regulatory body was poorlyrnstructured and regions have neither their own legislations nor regulatory bodies. Unavailabilityrnof guidelines for registration of traditional medicines, post-marketing surveillance and goodrnmanufacturing practice procedure, poor regulation of government owned entities and poorrncommunication of regulatory activities to the public were also shortcomings of the regulatoryrnsystem. Generally, limited regulatory legislations and tools and poor organizational structuresrnwere identified as the major gaps of the regulatory framework. Therefore, development andrnadoption of the lacking legislations and tools as well as re-structuring of the federal regulatoryrnbody and establishment of regional regulatory bodies should be done to strengthen the regulatoryrnframework.