Information technology is valuable in managing the supply chain of pharmaceuticals. Thernquality and utilization of information system are challenge. The aim of the study was to assessrnthe quality of data, the utilization practice of the health commodity management informationrnsystem and to identify contributing factors. The research was conducted in selected public healthrnfacilities at Addis Ababa, Ethiopia from April 10 to June 10, 2019. The design of the study was arndescriptive cross sectional study in which a mixed-method approach using quantitative andrnqualitative methods was employed. Five data quality dimensions: accuracy, completeness,rntimeliness, validity, and consistency were used to assess reports within the previous one year andrnutilization practice was also assessed. Data was collected using pre-tested questionnaires,rnthrough document reviews, in-depth interview, and key informants interview. Analysis wasrnperformed by using Statistical Package for Social Science version 25 software where descriptivernstatistics mainly: percentage, frequency, mean and standard deviation, and inferential statisticsrnlike spearman rho correlation was computed. Qualitative data were analyzed thematically.rnTwenty facilities were included in the study, where the overall data quality was 66.61%. All thernstudied facilities use the system for recording of activities. The average utilization of all thernregular reports was 39.17%. There were moderate positive correlations between data qualityrnwith the period of implementation (rrns rn= .512, P=.021, N=20) and database characteristics (rrns rn=.567, P=.001, N=30) and also, utilization practice with organizational factors (rrns rn= .601,rnP=.000, N=30). Health facilities need to improve their data quality and utilization practice.