Polymer Translocation Through Nanochannel - A Two Dimensional Monte Carlo Simulation Study

In this paper we investigate Monte Carlo(MC) simulation of polymer translocation throughrna nanochannel. To this end we used the Bond Fluctuation Method (BFM) to study therntranslocation process of a polymer chain of length N in two dimensions, in the absencernof external force on the polymer (i.e. unbiased translocation). To overcome the entropicrnbarrier we consider a polymer, in which the center monomer is initially placed in thernmiddle of the channel and study the escape time needed for the polymer to completelyrnexit the channel on either side of the end. Numerically we nd that the escape time rnscales with the chain length N as N1+2 , where is the Flory exponent as far as thernchannel is small enough. And this scaling preferably agree with the translocation timernof a polymer which passes through a nanopore in one direction only. In this work, wernexamine the interplay between the channel length L, width W and other parameters whilernsimulating the translocation processrnKeywords: Nanochannel, Translocation time, Escape time, DNA sequencing

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