Hepatoprotective Activity Of Aqueous And Ethanol Extract Of Lippia Adoensis Leaf Against Carbon Tetrachloride-induced Hepatotoxicity In Mice
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Medicinal plants may be the best source of remedies for the treatment of liver disease. Thus identification of a potential therapeutic agent for protection of liver from hepatotoxins provides a useful way for the prevention of liver related illnesses. The aim of the present study was to investigate the hepatoprotective activity of 80% ethanolic and aqueous extract of leaves of Lippia adoensis against carbontetrachloride in mice.rnMice were pretreated with extract of Lippia adoensis (200 & 400 mg/kg bw.po) for 7 days and then challenged with CCl4 (2ml/kg bw po.) on the 7th day. Serum biomarkers (AST, ALT, ALP and total bilirubin, total protein and albumin) were estimated in all the study groups. Alteration in the levels of biochemical parameters of hepatic damage like AST, ALT, ALP and total bilirubin, total protein and albumin were tested in both CCl4 and Lippia adoensis extract treated groups. CCl4 significantly (P
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