Chromosome numbers are reported here for 11 species of the Lamiaceaernbelonging to 6 genera. Two of the species, Satureja paradoxa and Thymusrnschimperi, are endemic to Ethiopia. Chromosome preparations were madernfrom root tip cells after pretreatment with colchicine or 8-hydroxyquinolinernor cold treatment in ice water. Maceration was done in 4% cellulase + 4%rnpectinase solution at 36-370C for about one hour which was followed byrnairdry slide preparation. Chromosomes were stained with Giemsa inrnSorensen’s phosphate buffer (pH=6.8). The following 2n chromosomernnumbers were observed for the studied eleven species: Ajuga integrifolia,rn2n=64; Ocimum basilicum var. basilicum, 2n=50; O. lamiifolium, 2n=42;rnPlectranthus caninus, 2n=30; P. ornatus, 2n=30; P. punctatus, 2n=56; P.rnpseudomarrubioides, 2n=64; Salvia nilotica, 2n=32; Satureja paradoxa,rn2n=32; S. simensis, 2n=22; and Thymus schimperi, 2n=30. Thernchromosome numbers were determined from somatic mitotic chromosomesrnat early prophase to metaphase stages. Polyploidy is evident in most of thernspecies. Variable basic chromosome numbers for species of the same genusrnwere observed. Detailed studies of chromosome morphology were notrnpossible because of the small size of the chromosomes. Notes on therntaxonomy and distribution of each of the genera and species under thisrnstudy are provided. It was recommended that further cytogenetical studiesrnof many species of the family occurring in Ethiopia are required for betterrnunderstanding of the phylogenetic and evolutionary relationships of the genera and species.