Background: Significant numbers of people with cancer develop mental health problems atrndifferent stages of the disease.Psychological/psychiatric treatment is part of palliative care thatrnis given to people with cancer to make them be able to deal with their problem individuallyrnand as a family. The Oncology unit atTASRHis known to be the only cancer referral center inrnthe country. Published data done in Ethiopia were not found on how health care professionalsrnin the oncology units understandassess or address mental health needs of people with cancerrnand the obstacles they encounter. rnObjective: This study aims to explore the cliniciansâ€Ÿ perspective of mental health needs ofrnpeople with advanced cancer and the strategies clinicians use to assess and address thosernneeds in TASRHOncology follow-up clinic. rnMethod: An exploratory qualitative research design was employed and participants werernselected purposively based on years of experience. Data was collected, transcribed inrnAmharic, translated to English and then analyzed through thematic analysis. The study wasrnconducted at TASRH, October 2018.rnResults: Majority of the participants reported to notice some mental health problems inrnpatients with cancer but have some difficulty to identify symptoms and provide first linerntreatments. All participants stated that it is advantageous for patients to know about theirrnillness. Participants also suggest the disadvantages patients from knowing about their illnessrnis mainly due to the ways of information delivery. The increased number of patients visitingrnthe clinic on daily basis was a major obstacle. rnConclusion:Timely and accurate diagnosis of co morbid mental disorders and addressingrnpsychosocial factors is required to increase quality of life of people with cancer.