Objective: Burnout has a significant negative impact on the employees,rnservice provided to patients and the organization. As there are no datarnon burnout among staff in Amanuel Specialized Mental Hospital, thisrnstudy sought to document the prevalence of burnout among theclinicalrnstaff at the hospital.rnMethods: This was a cross sectional study of clinical staff working atrnAmanuel specialized Mental Hospital. The hospital staff completed selfadministeredrnquestionnaires on socio-demographic characteristics andrnwork related features, and the Maslach Burnout Inventory â€“ HumanrnServices and General Survey, and Oslo social support scale. Analysis ofrnthe data was undertaken using the Statistical Package for the SocialrnSciences (SPSS) version 21.0.rnResults: 40.5% percent of the respondents reported moderate to highrnlevel of emotional exhaustion while 45.8% reported moderate tornhighlevel of depersonalization. Low level of personal accomplishmentrnwas reported by 36.6%. The number of out-patients seen and malerngender were positively associated with depersonalization. The level ofrnsocial support wasassociated with both depersonalization andrnemotional exhaustion. Staff made several recommendations how torndecrease burnout among the staff.rnConclusion: Significant levels of burnout were reported. These shouldrnbe addressed at an individual, and institutional levels. More studies arernneeded to identify the risk factors.