Introduction: Soft tissue is the supportive tissue of various organs and the non-epithelial, extra rnskeletal structures exclusive of lympho-hematopoietic tissues. It includes fibrous connectiverntissue, adipose tissue, skeletal muscle, blood/lymph vessels, and the peripheral nervous system.rnMost soft tissue tumors are classified as ether benign and malignant there are also intermediaterngroups implying aggressive local behavior with low to moderate probability for metastasis. Softrntissue tumors are classified histologically on the basis of the adult tissue they resemble.rnObjective: Assessment of radio-pathologic correlation of soft tissue tumors in patients evaluatedrnat Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia 2019. rnMethod: The study was conducted at TASH from May 2018-January 2019. Hospital based rnprospective cross sectional study was conducted at TASH to address the specific objective duringrnstudy period. The Study was conducted among patients being evaluated at Tikur AnbessarnSpecialized Hospital oncology department who have both MRI and pathology result during studyrnperiod. Data was collected by evaluating the MRI report and biopsy result from oncologyrndepartment and also using structured questionnaires. The data was checked for clarity andrncompleteness. Computerized data analysis was conducted by using SPSS version 25 software. rnResult: Total of 73 cases evaluated with 60% malignant. The sensitive MRI parameters forrnmalignancy are size >5cm (91%), necrosis (82%), bone involvement (80%). The specific MRIrnparameters include age>25yr (86%), necrosis (78%), heterogeneous enhancement (75%). From allrnthe MRI parameters only necrosis had significant correlation with malignancy on imaging in ourrnstudy.rnConclusion: The most sensitive and specific MRI parameter to predict malignancy in our studyrnare size > 5cm, necrosis, heterogeneous enhancement. Necrosis had significant correlation forrnmalignancy.