The Sensitivity Of Chest Ct For The Diagnosis Of Covid-19 Pneumonia And Imaging Patterns As Seen On Chest Ct A Crossectional Prospective Study Done In Addis Ababa
Background: rnCoronavirus disease 2019 (COVID-19) is a respiratory illness caused by a novel coronavirusrndesignated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).rn The infectionrnwidely and rapidly spread all over the world with significant impacts upon the sociopolitical milieurnand healthcare delivery systems. On 11 March 2020 COVID-19 was declared a pandemic by WHO rn(2)rnand on March 13, 2020, the first confirmed COVID-19 case was reported in Ethiopia. Thernclinical presentation spectrum varies and includes mild to moderate symptoms, severe symptoms,rnand critical illness.rn(2)rn Although RT PCR test has been considered to be the gold standard, chestrnimaging especially has an adjunct role not only in the diagnosis but in the assessment of thernseverity of the disease and identification of complications.rn(3)rn Identification of the typical imagingrnpattern and degree of involvement is important to guide and plan treatment. rnObjective: The study was conducted to assess the sensitivity of chest CT scan as compared to thernstandard RT PCR for the diagnosis of COVID-19 and also to determine the different chest CT rnimaging patterns and severity of COVID-19 pneumonia. rnMethod: A crossectional study was conducted based on data collected from different diagnosticrncenters and treatment centers from July 1, 2021, to October 1, 2021. The chest CT of the patients rnwas reviewed and a structured questionnaire was filled on a Google form sheet. The data werernexported and analyzed on SPSS version 26. rnResult: Among a total of 193 patients included in this study, 116 (60.1%) were males and 77rn(39.9%) were females with a mean (SD) age of 50±14.2 years. Among patients for whom data rnregarding previously known comorbidities was available hypertension and diabetes mellitusrnaccounted for 26 (61.9%), and 25 (59.5%) respectively. Of 107 patients whose presentingrncomplaints were available, cough was the most common complaint seen in 82 (76%) of thernpatients, followed by shortness of breath in 65 (60.7%), chest pain in 36 (33.6%), and fatigue inrn26 (24.3%). Using the RT PCR result as a gold standard the sensitivity, and specificity of chestrnCT were found to be 82.9 % and 16.7% respectively. The chest CT distribution showed that 95.9%rnof the cases were bilateral and 51.3 % had a peripheral distribution. Among the typical chest CT rnpatterns, 157(83%) of the CT images showed GGO, 152(80.4%) consolidation, and 68(35.4%)rnshowed broncho-vascular thickening. rnThe mean chest CT severity score was 13.6±6.2 and 95 (49.2%) patients had a score of >18rn(severe). A positive correlation was identified between CT severity score with age and diabetesrnwith a P-value < 0.01. rnConclusion: This study demonstrated that chest CT has a high sensitivity (82.9%) in therndiagnosis of COVID-19 pneumonia. Ground glass opacity, consolidation, and bronchovascular rnthickening were the predominant features seen with a predominant bilateral, basal, and peripheralrndistribution. The study also revealed chest CT severity score is positively correlated with age andrncomorbidity of DM.