The purpose of the axle is one of the most important components of a rail vehicle whichrntransmits the weight of the vehicle to the wheels, meets the vertical and horizontal loadsrnformed during static and dynamic moving, and carries the driving moment and brakingrnmoment, since it is subjected to rotating bending and the issue of fatigue failure always existrn.The main objective of this thesis is to one investigation of fatigue failure in railway frontrnaxle using finite element analysis. One of the most loaded axle locomotives are driving axles,rnwhich are subjected to simultaneous bending and twisting (while driving â€“ especially duringrnacceleration and braking) and the same bending (when stationary). Fatigue failures start atrnthe most vulnerable point in a dynamically stressed area particularly where there is a stressrnraiser (discontinuities or change in diameter). Investigation and analyzing manually isrntedious. Hence FEM is very accurate to analyzing and designing. FEM shows the mostrncritical part of the axle to analyze the failures and also has available fatigue tool. Modelingrnof railway front axle to study fatigue failure under different loads using CATIA & ANSYSrnsoftware is done. In addition parametric study to investigate the effect of loading conditionrnin axles, estimation of fatigue life in working condition in railway front axle by finite elementrnmethod using ANSYS Workbench software. By using FE M and numerical analysis therncritical part of load that cause failure is investigated. Endurance limit, fatigue factor of safetyrnand the theoretical no of cycles sustained by the axle before failure is estimated. Inrnconclusion the increase in fillet radii of the axle and change in the position of the supportrndecreases the stress concentration factor, increase the endurance limit and fatigue factor ofrnsafety of the axle.