The objective of this study was to studying the influence of TV alcohol ads exposure on adolescents alcohol use. A questionnaire, including five-point scale items, was designed based on previous research and distributed to two hundred thirty six (109 males and 127 females) Kokebe Tsibah preparatory school students. Focus group discussion was also conducted with thirteen discussants. The participants were selected using stratified random sampling method. The findings of this study revealed that watching TV alcohol advertisements is related with alcohol use. Gender of the adolescents was also strongly related with alcohol use. Male participants, compared to females, scored high on likability, identification and expectancy scale items; hence they were more likely to use alcohol as compared to their female counterparts. The result also revealed that likability of ads, identification of teenagers with characters of TV alcohol ads and expectancy to use alcohol derive teenagers to use alcohol. Moreover, likability of alcohol TV ads, identification of teenagers with models of alcohol ads and expectancy of alcohol use were found to be significant predictors of alcohol use. In addition, the result from qualitative data also showed that TV alcohol commercials encouraged adolescents to use alcohol by showing, music, dance, humor and youthful lifestyle on TV alcohol ads. Moreover, adolescents perceived drinking alcohol use as healthy lifestyle due to the fact those advertisers sent only positive outcomes of alcohol. Based on the findings of the study it has been recommended that design counter-advertising targeting at younger age by incorporating elements such as music, humor and youth-attractive characters that appeal to these audiences may reduce the unwanted impacts of TV alcohol ads.