The objective of the study was assessing the knowledge, attitudes and practices about domestic adoption and foster care services among Commercial Bank of Ethiopia employees in Addis Ababa. The data was collected from 250 randomly selected participants. The data collected were analyzed using both descriptive and inferential statistics. The instruments used for data collection included questionnaires and interviews. The researcher used mixed research design for this study. The result revealed that the participantsâ€™ have knowledge about the meaning of domestic adoption but have low practices of the adoption and foster care service. They have also negative attitude towards domestic adoption and foster care service. Knowledge of domestic adoption was not different between males (M = 4.176, SD = 2.09, n = 159) and females (M = 3.86, SD = 1.38, n = 91) at the .05 level of significance t (248) = 1.256, p> .05, 95% CI [-.175 to .791]; but knowledge of foster care was different between males (M = 3.69, SD = 2.10, n = 159) and females (M = 3.12, SD = 1.56, n = 91) at the .05 level of significance t (248) = 2.440, p< .05, 95% CI [.11 to 1.04]. There is no statistically significant difference at the p> .05 level for the age categories of adoption knowledge: F (3, 246) = 1.313, p = .271; Foster care knowledge: F (3, 246) = 2.481, p = .062; and adoption attitude: F (3, 246) = 2.619, p = .051, but statistically significant difference at the p< .05 level in foster care attitude: F (3, 246) = 3.694, p = .013; domestic adoption practice: F (3, 246) = 9.164, p = .001; foster care practice: F(3, 246) = 8.63, p = .001). There is no statistically significant difference at the p> .05 level for the level of education categories of adoption practice: F (3, 246) = 2.132, p = .097, adoption knowledge: p = .387. Even though there were a few practices of domestic adoption and foster care services among the participants, for most of them, especially foster care is the new concept.rnKey words: knowledge, attitude, practices, adoption, foster care service