Sign language is a formal language, socially agreed on, rule â€“governed symbol systemrnthat is generative in nature. The components of sign language are not phonemic (sound)rncombinations that movement at form words, at spoken language, but rather phonologicalrncombinations (i.e. hand shapes, form signs (Mccanally, 1994).rnThe main purpose of this study is to assess the Ethiopian sign language using for thernteaching purposes in five regional states of Ethiopia. In order to meet this purpose 31,rnrespondents selected based on judgment sampling. The required data were collectedrnthrough interviews, videotape, and classroom observation and text analysis.rnThe result of the study was analyzed qualitatively. The result of the study shows that thernhearing-impaired students and their teachers seem to fail to establish commonrnunderstanding because of lack of sign language for technical and scientific environmentalrnscience and chemistry terminologies.rnLack of adequate skills on sign language on the part of the teachers as well as deafrnstudents and sign language interpreterâ€Ÿs complexity and uniformity of sign language usedrnby most of the hearing-impaired students in five regional states of Ethiopia.rnAs indicated by this research, there is wide variation from region to region in the use ofrnEthiopian sign language in environmental science and grade 11 chemistry subjects.rnFailure communication exists among students and, more over, between students andrnteachers. The Sign language variations are also seen among teachers, interpreters, andrnstudents.rnFinally : the study recommends continuous training of sign language for teachers andrninterpreters, Laboratory and resources should be available at high school and universityrnlevels, encourage creating new sign and experience sharing , prepare sign languagerndictionary in different subjects and further researcher must be done