The pwpose of this study was to identify and analyze the major challenges andrnopportunities in implementing NFBE program in South Eastern Zone ofTigray RegionalrnState. A descriptive survey research method was employed for the purpose. Ten NFBErncenters ji'om two weredas (Enderta and Degua Tembien) were selected as subjets of thernstudyA total of 128 respondents, 60 adult learners,30 facilitators, 5 supervisors, 8 Tabiarnmanagers, 2 sector heads, 2 education experts, 20 non-participant adults,l educationrnoffice head, participated as source of data. Pwposive, accidental, random andrnavailability sdmpling were used as sampling techniques. The data were gathered byrnmeans of ji'om document analysis, observation, questionnire and interviews. In analyzingrnthe data percentage, mean and rank order were used. The findings of the study indicatesrnthe existence of both opportunities and challeng The involvement of adult learners in thernselecton of NFBE centers, deciding the schedule and ji'equent exercise of learnerrncentered approach were found to be major opportunity of the program. The identifiedrnproblems were lack of community parficipation in preparing a plan and selection ofrnfacilitators, the absence of training and paymel1l for jhcilitators, inadllqllacy ojrneducational resources and facilities, low enrollmel1l rate, high dropout rate, poorrnutilization of teaching aids, lack ofmonitiring and evalliatiol1. Hence, if can be conludedrnthat the NFBE program in South Eastern Zone of Tigray was highlyrnmarginilized. Therefore, it is recommended that the 11'ereda education office sufficientrnshould provide aducate material and technical assistance to the centers. There must bernpropel' monitoring and evaluafion of the over all activities of the centers with activerninvolvement of stakeholders. To ensure fhe sustainability of the program, fhe weredarneducation office have to negotiatew with NCOs and local communities to support thernprogram with adequate financial resources.