In Ethiopia, most wastewater effluent is directly released in to rivers. Kebena River is one of the rivers, which is affected by municipal wastewater generated from different households, hospitals, hotels of Addis Ababa city. The study was conducted to evaluate and map water quality status of Kebena River from upstream (Entoto) up to the downstream (Saris Abo). Water quality index was used to analyze the overall water quality status. The water quality index was determined by considering 11 parameters at 28 station (i.e. total of 308) tastes were obtained. The outcome of the study showed that two sample points at the upstream part of the river is relatively in good conditions. Three out of the twenty-eight sample points have acceptable quality and the remaining sites have shown unsuitable result.rnLaboratory result for each(11) parameter indicates that the range of PH(6.35-7.67mg/l), Electricconductivity(433_1425us/cm),Totalcoliform(22_2292mg/l),Dissolvedoxgen(0.1_4.4mg/l),COD(12_649mg/l),Nitrite(